Author's response to reviews Title: Predicting nicotine dependence profiles among adolescent smokers: The roles of personal and social-environmental factors in a longitudinal framework Authors:

1. The objectives as described in the abstract are very general, whereas the introduction suggests that the researchers are testing a specific hypothesis about personality characteristics. The objectives in the abstract should be re-worked to match those in the introduction. We thank the reviewer for this suggestion. The objective is rephrased as follows: “The objective of the present study is to identify the effects of theoretically driven social and individual predictors of nicotine dependence symptom profiles in a population-based sample of adolescent smokers.” 2. Please describe the 4 dependence profiles in the abstract The 4 dependence profiles are now mentioned in the abstract 3. How specifically do these results inform interventions? We rephrased the last sentence: “It is recommended that intervention programs more specifically target individuals with a high risk of developing more severe dependence symptom profiles.”